Cochrane review of first line drugs for hypertension

Journal Ref. Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G: Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000, 342:145-153.
Intervention Drug - anti-hypertension drug
Number of sites 282
Countries involved USA, Mexico, Brazil, Europe etc
Sample size 9297
Type of statistical analyses
Risk of bias Overall: Low Risk details
Duration of trial
Primary outcome mortality
Show Score Ranges


(shows median if more than one score was entered)

Elig. Recr. Setting Org. Int. Flex. Del. Flex. Adherence Follow-Up Prim. Out. Prim. An.
2 3 5 3 3 3 3 2 5