Cochrane systematic review of first line treatment for hypertension

Journal Ref. Rationale and design of a randomized clinical trial on prevention of stroke in isolated systolic hypertension. The Systolic Hypertension in the Elderly Program (SHEP) Cooperative Research Group. J Clin Epidemiol 1988, 41:1197-1208.
Intervention Drug - Anti-hypertensive
Number of sites 16
Countries involved USA
Sample size 4736
Type of statistical analyses
Risk of bias Overall: Low Risk details
Duration of trial
Primary outcome Stroke fatal and non fatal
Show Score Ranges


(shows median if more than one score was entered)

Elig. Recr. Setting Org. Int. Flex. Del. Flex. Adherence Follow-Up Prim. Out. Prim. An.
1 1 1 1 2 3 1 3 5