Cochrane systematic review for first line treatment for hypertension

Journal Ref. Staessen JA, Fagard R, Thijs L, Celis H, Arabidze GG, Birkenhager WH, Bulpitt CJ, de Leeuw PW, Dollery CT, Fletcher AE, et al: Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Lancet 1997, 350:757-764.
Intervention Drug - anti-hypertensives
Number of sites 198
Countries involved East and West Europe
Sample size 4695
Type of statistical analyses
Risk of bias Overall: Low Risk details
Duration of trial
Primary outcome Stroke
Show Score Ranges


(shows median if more than one score was entered)

Elig. Recr. Setting Org. Int. Flex. Del. Flex. Adherence Follow-Up Prim. Out. Prim. An.
1 5 5 3 4 5 2 3 5